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Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice

Alagille syndrome, a chronic hepatobiliary disease, is characterized by paucity of intrahepatic bile ducts (IHBDs). To determine the impact of Notch signaling specifically on IHBD arborization we studied the influence of both chronic gain and loss of Notch function on the intact three-dimensional IH...

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Bibliographische Detailangaben
Hauptverfasser: Sparks, Erin E., Huppert, Kari A., Brown, Melanie A., Washington, M. Kay, Huppert, Stacey S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995854/
https://ncbi.nlm.nih.gov/pubmed/20069650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23431
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