Novel Insights Regarding the Operational Characteristics and Teleological Purpose of the Renal Na(+)-K(+)-Cl(2) Cotransporter (NKCC2s) Splice Variants

The absorptive Na(+)-K(+)-Cl(−) cotransporter (NKCC2) is a polytopic protein that forms homooligomeric complexes in the apical membrane of the thick ascending loop of Henle (TAL). It occurs in at least four splice variants (called B, A, F, and AF) that are identical to one another except for a short...

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Main Authors: Brunet, Geneviève M., Gagnon, Edith, Simard, Charles F., Daigle, Nikolas D., Caron, Luc, Noël, Micheline, Lefoll, Marie-Hélène, Bergeron, Marc J., Isenring, Paul
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266623/
https://ncbi.nlm.nih.gov/pubmed/16157691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509334
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