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Defining the Retinoid Binding Site in the Rod Cyclic Nucleotide-gated Channel
Rod vision is initiated when 11-cis-retinal, bound within rhodopsin, absorbs a photon and isomerizes to all-trans-retinal (ATR). This triggers an enzyme cascade that lowers cGMP, thereby closing cyclic nucleotide-gated (CNG) channels. ATR then dissociates from rhodopsin, with bright light releasing...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2266610/ https://ncbi.nlm.nih.gov/pubmed/16230468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509387 |
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