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Long Polyamines Act as Cofactors in PIP(2) Activation of Inward Rectifier Potassium (Kir2.1) Channels

Phosphatidylinosital-4,5-bisphosphate (PIP(2)) acts as an essential factor regulating the activity of all Kir channels. In most Kir members, the dependence on PIP(2) is modulated by other factors, such as protein kinases (in Kir1), G(βγ) (in Kir3), and the sulfonylurea receptor (in Kir6). So far, ho...

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Autors principals: Xie, Lai-Hua, John, Scott A., Ribalet, Bernard, Weiss, James N.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266595/
https://ncbi.nlm.nih.gov/pubmed/16316973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509380
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