Fatty Acid Transduction of Nitric Oxide Signaling: MULTIPLE NITRATED UNSATURATED FATTY ACID DERIVATIVES EXIST IN HUMAN BLOOD AND URINE AND SERVE AS ENDOGENOUS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR LIGANDS

Mass spectrometric analysis of human plasma and urine revealed abundant nitrated derivatives of all principal unsaturated fatty acids. Nitrated palmitoleic, oleic, linoleic, linolenic, arachidonic and eicosapentaenoic acids were detected in concert with their nitrohydroxy derivatives. Two nitroalken...

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Detalhes bibliográficos
Main Authors: Baker, Paul R. S., Lin, Yiming, Schopfer, Francisco J., Woodcock, Steven R., Groeger, Alison L., Batthyany, Carlos, Sweeney, Scott, Long, Marshall H., Iles, Karen E., Baker, Laura M. S., Branchaud, Bruce P., Chen, Yuqing E., Freeman, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266087/
https://ncbi.nlm.nih.gov/pubmed/16227625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M504212200
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