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Over-expression of the bovine FcRn in the mammary gland results in increased IgG levels in both milk and serum of transgenic mice

The neonatal Fc receptor (FcRn) protects immunoglobulin G (IgG) from catabolism and is also responsible for IgG absorption in the neonatal small intestine. However, whether it mediates the transfer of IgG from plasma to milk still remains speculative. In the present study, we have generated transgen...

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Detalhes bibliográficos
Main Authors: Lu, Wei, Zhao, Zhihui, Zhao, Yaofeng, Yu, Shuyang, Zhao, Yiqiang, Fan, Baoliang, Kacskovics, Imre, Hammarström, Lennart, Li, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266012/
https://ncbi.nlm.nih.gov/pubmed/17608809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02654.x
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