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Altered editing in RNA editing adenosine deaminase ADAR2 gene transcripts of systemic lupus erythematosus T lymphocytes

Adenosine Deaminases that act on RNA (ADARs) edit gene transcripts through site-specific conversion of adenosine to inosine by hydrolytic deamination at C6 of the adenosine. ADAR2 gene transcripts are substrates for the ADAR1 and ADAR2 enzymes and their expression is regulated by editing at the − 1...

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Bibliographische Detailangaben
Hauptverfasser: Laxminarayana, Dama, O'Rourke, Kenneth S, Maas, Stefan, Olorenshaw, Irene
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2007
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265949/
https://ncbi.nlm.nih.gov/pubmed/17376196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02582.x
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