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Toll-like receptor interactions: tolerance of MyD88-dependent cytokines but enhancement of MyD88-independent interferon-β production

Toll-like receptors (TLRs) signal through two main pathways: a myeloid differentiation factor (MyD)88-dependent pathway that acts via nuclear factor κB (NF-κB) to induce proinflammatory cytokines such as tumour necrosis factor-α (TNF-α) and a MyD88-independent pathway that acts via type I interferon...

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Hlavní autoři: Broad, Andrea, Kirby, John A, Jones, David E J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Inc 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265871/
https://ncbi.nlm.nih.gov/pubmed/17034424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02485.x
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