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MEKK3 is essential for lipopolysaccharide-induced interleukin-6 and granulocyte–macrophage colony-stimulating factor production in macrophages

Mitogen-activated protein/ERK kinase kinase 3 (MEKK3) is a Ser/Thr protein kinase belonging to the MEKK/STE11 subgroup of the MAP3K family. Recently, we found that MEKK3 plays a critical role in interleukin-1 (IL-1) receptor and Toll-like receptor 4 signalling using established primary mouse embryon...

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Autori principali: Kim, Kihwan, Duramad, Omar, Qin, Xiao-Feng, Su, Bing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265862/
https://ncbi.nlm.nih.gov/pubmed/17116170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02495.x
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