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The effects of a partitioned var gene repertoire of Plasmodium falciparum on antigenic diversity and the acquisition of clinical immunity

BACKGROUND: The human malaria parasite Plasmodium falciparum exploits antigenic diversity and within-host antigenic variation to evade the host's immune system. Of particular importance are the highly polymorphic var genes that encode the family of cell surface antigens PfEMP1 (Plasmodium falci...

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Autori principali: Recker, Mario, Arinaminpathy, Nimalan, Buckee, Caroline O
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265724/
https://ncbi.nlm.nih.gov/pubmed/18215289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-18
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