Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates

BACKGROUND: Var genes encode a family of virulence factors known as PfEMP1 (Plasmodium falciparum erythrocyte membrane protein 1) which are responsible for both antigenic variation and cytoadherence of infected erythrocytes. Although these molecules play a central role in malaria pathogenesis, the m...

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Hlavní autoři: Kraemer, Susan M, Kyes, Sue A, Aggarwal, Gautam, Springer, Amy L, Nelson, Siri O, Christodoulou, Zoe, Smith, Leia M, Wang, Wendy, Levin, Emily, Newbold, Christopher I, Myler, Peter J, Smith, Joseph D
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805758/
https://ncbi.nlm.nih.gov/pubmed/17286864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-45
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