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A Randomization Test for Controlling Population Stratification in Whole-Genome Association Studies

Population stratification can be a serious obstacle in the analysis of genomewide association studies. We propose a method for evaluating the significance of association scores in whole-genome cohorts with stratification. Our approach is a randomization test akin to a standard permutation test. It c...

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Detalhes bibliográficos
Main Authors: Kimmel, Gad , Jordan, Michael I. , Halperin, Eran , Shamir, Ron , Karp, Richard M. 
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Human Genetics 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265648/
https://ncbi.nlm.nih.gov/pubmed/17924333
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