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GADD45A Does Not Promote DNA Demethylation

Although DNA methylation patterns in somatic cells are thought to be relatively stable, they undergo dramatic changes during embryonic development, gametogenesis, and during malignant transformation. The enzymology of DNA methyltransferases is well understood, but the mechanism that removes methylat...

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Detalhes bibliográficos
Main Authors: Jin, Seung-Gi, Guo, Cai, Pfeifer, Gerd P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265528/
https://ncbi.nlm.nih.gov/pubmed/18369439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000013
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