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GADD45A Does Not Promote DNA Demethylation

Although DNA methylation patterns in somatic cells are thought to be relatively stable, they undergo dramatic changes during embryonic development, gametogenesis, and during malignant transformation. The enzymology of DNA methyltransferases is well understood, but the mechanism that removes methylat...

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Bibliografiske detaljer
Main Authors: Jin, Seung-Gi, Guo, Cai, Pfeifer, Gerd P.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265528/
https://ncbi.nlm.nih.gov/pubmed/18369439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000013
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