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Intrinsically Disordered Proteins Display No Preference for Chaperone Binding In Vivo
Intrinsically disordered/unstructured proteins (IDPs) are extremely sensitive to proteolysis in vitro, but show no enhanced degradation rates in vivo. Their existence and functioning may be explained if IDPs are preferentially associated with chaperones in the cell, which may offer protection agains...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265518/ https://ncbi.nlm.nih.gov/pubmed/18369417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000017 |
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