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NFAT but not NF-κB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells
FcϵRI-activation–induced survival of mast cells is dependent on the expression and function of the prosurvival protein A1. The expression of A1 in lymphocytes and monocytes has previously been described to be transcriptionally regulated by NF-κB. Here we demonstrate that the expression of A1 in mast...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265451/ https://ncbi.nlm.nih.gov/pubmed/18182578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-053371 |
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