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NFAT but not NF-κB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells

FcϵRI-activation–induced survival of mast cells is dependent on the expression and function of the prosurvival protein A1. The expression of A1 in lymphocytes and monocytes has previously been described to be transcriptionally regulated by NF-κB. Here we demonstrate that the expression of A1 in mast...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ullerås, Erik, Karlberg, Mats, Möller Westerberg, Christine, Alfredsson, Jessica, Gerondakis, Steve, Strasser, Andreas, Nilsson, Gunnar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265451/
https://ncbi.nlm.nih.gov/pubmed/18182578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-053371
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