Transmission of HIV-1 CTL Escape Variants Provides HLA-Mismatched Recipients with a Survival Advantage

One of the most important genetic factors known to affect the rate of disease progression in HIV-infected individuals is the genotype at the Class I Human Leukocyte Antigen (HLA) locus, which determines the HIV peptides targeted by cytotoxic T-lymphocytes (CTLs). Individuals with HLA-B*57 or B*5801...

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Autori principali: Chopera, Denis R., Woodman, Zenda, Mlisana, Koleka, Mlotshwa, Mandla, Martin, Darren P., Seoighe, Cathal, Treurnicht, Florette, de Rosa, Debra Assis, Hide, Winston, Karim, Salim Abdool, Gray, Clive M., Williamson, Carolyn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265427/
https://ncbi.nlm.nih.gov/pubmed/18369479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000033
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