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Myoblasts and macrophages share molecular components that contribute to cell–cell fusion

Cell–cell fusion is critical to the normal development of certain tissues, yet the nature and degree of conservation of the underlying molecular components remains largely unknown. Here we show that the two guanine-nucleotide exchange factors Brag2 and Dock180 have evolutionarily conserved functions...

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Autors principals: Pajcini, Kostandin V., Pomerantz, Jason H., Alkan, Ozan, Doyonnas, Regis, Blau, Helen M.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265408/
https://ncbi.nlm.nih.gov/pubmed/18332221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707191
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