Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients

OBJECTIVE: To investigate whether variable antidepressant response may be influenced by an interaction between the serotonin transporter promoter polymorphism (5-HTTLPR) and antidepressant concentration. METHODS: Elderly subjects with depression treated with paroxetine (n = 110) were genotyped and a...

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Detaylı Bibliyografya
Asıl Yazarlar: Lotrich, Francis E., Pollock, Bruce G., Kirshner, Margaret, Ferrell, Robert F., Reynolds III, Charles F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Canadian Medical Association 2008
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265313/
https://ncbi.nlm.nih.gov/pubmed/18330458
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