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A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo

The transmembrane precursor of tumor necrosis factor-α (TNF) exits the trans-Golgi network (TGN) in tubular carriers for subsequent trafficking and delivery to the cell surface; however, the molecular machinery responsible for Golgi export is unknown. We previously reported that members of the TGN g...

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Autors principals: Lieu, Zi Zhao, Lock, John G., Hammond, Luke A., La Gruta, Nicole L., Stow, Jennifer L., Gleeson, Paul A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265200/
https://ncbi.nlm.nih.gov/pubmed/18308930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800137105
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