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Nanometer-scale mapping and single-molecule detection with color-coded nanoparticle probes

We report a method for single-molecule detection and biomolecular structural mapping based on dual-color imaging and automated colocalization of bioconjugated nanoparticle probes at nanometer precision. In comparison with organic dyes and fluorescent proteins, nanoparticle probes such as fluorescenc...

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Detalhes bibliográficos
Main Authors: Agrawal, Amit, Deo, Rajesh, Wang, Geoffrey D., Wang, May D., Nie, Shuming
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265145/
https://ncbi.nlm.nih.gov/pubmed/18305159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712351105
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