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Gating at the selectivity filter in cyclic nucleotide-gated channels

By opening and closing the permeation pathway (gating) in response to cGMP binding, cyclic nucleotide-gated (CNG) channels serve key roles in the transduction of visual and olfactory signals. Compiling evidence suggests that the activation gate in CNG channels is not located at the intracellular end...

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Autori principali: Contreras, Jorge E., Srikumar, Deepa, Holmgren, Miguel
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265121/
https://ncbi.nlm.nih.gov/pubmed/18287006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709809105
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