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Plx1 is required for chromosomal DNA replication under stressful conditions
Polo-like kinase (Plk)1 is required for mitosis progression. However, although Plk1 is expressed throughout the cell cycle, its function during S-phase is unknown. Using Xenopus laevis egg extracts, we demonstrate that Plx1, the Xenopus orthologue of Plk1, is required for DNA replication in the pres...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265110/ https://ncbi.nlm.nih.gov/pubmed/18309293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.29 |
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