Bacteriorhodopsin chimeras containing the third cytoplasmic loop of bovine rhodopsin activate transducin for GTP/GDP exchange

The mechanisms by which G-protein-coupled receptors (GPCRs) activate G-proteins are not well understood due to the lack of atomic structures of GPCRs in an active form or in GPCR/G-protein complexes. For study of GPCR/G-protein interactions, we have generated a series of chimeras by replacing the th...

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Main Authors: Geiser, Andrew H., Sievert, Michael K., Guo, Lian-Wang, Grant, Jennifer E., Krebs, Mark P., Fotiadis, Dimitrios, Engel, Andreas, Ruoho, Arnold E.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265101/
https://ncbi.nlm.nih.gov/pubmed/16815918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062192306
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