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Caspase-dependent activation of cyclin-dependent kinases during Fas-induced apoptosis in Jurkat cells

The activation of cyclin-dependent kinases (cdks) has been implicated in apoptosis induced by various stimuli. We find that the Fas-induced activation of cdc2 and cdk2 in Jurkat cells is not dependent on protein synthesis, which is shut down very early during apoptosis before caspase-3 activation. I...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Bin-Bing, Li, Honglin, Yuan, Junying, Kirschner, Marc W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22635/
https://ncbi.nlm.nih.gov/pubmed/9618490
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