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Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans

The initiation of transcription and replication of influenza A virus requires the 5' and 3' ends of vRNA. Here, the role of segment-specific non-coding sequences of influenza A virus on viral RNA synthesis was studied. Recombinant viruses, with the nonstructural protein (NS) segment-specif...

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Detalhes bibliográficos
Main Authors: Ng, Stella SF, Li, Olive TW, Cheung, Timothy KW, Malik Peiris, J S, Poon, Leo LM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2263042/
https://ncbi.nlm.nih.gov/pubmed/18186945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-2
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