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Protein tyrosine phosphatase-1B (PTP1B) helps regulate EGF-induced stimulation of S-phase entry in human corneal endothelial cells

PURPOSE: Human corneal endothelial cells (HCEC), particularly from older donors, only proliferate weakly in response to EGF. The protein tyrosine phosphatase, PTP1B, is known to negatively regulate EGF-induced signaling in several cell types by dephosphorylating the epidermal growth factor receptor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ishino, Yutaka, Zhu, Cheng, Harris, Deshea L., Joyce, Nancy C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Molecular Vision 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2263008/
https://ncbi.nlm.nih.gov/pubmed/18253097
Tagiau: Ychwanegu Tag
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