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Role of Insulin Receptor and Balance in Insulin Receptor Isoforms A and B in Regulation of Apoptosis in Simian Virus 40-immortalized Neonatal Hepatocytes

We have investigated the unique role of the insulin receptor (IR) and the balance of its isoforms A and B in the regulation of apoptosis in simian virus 40 (SV40)-immortalized neonatal hepatocytes. Immortalized hepatocytes lacking (HIR KO) or expressing the entire IR (HIR LoxP), and cells expressing...

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Autors principals: Nevado, Carmen, Benito, Manuel, Valverde, Angela M.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262979/
https://ncbi.nlm.nih.gov/pubmed/18172021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-05-0473
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