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Analysis of the transcriptional activity of endogenous NFAT5 in primary cells using transgenic NFAT-luciferase reporter mice

BACKGROUND: The transcription factor NFAT5/TonEBP regulates the response of mammalian cells to hypertonicity. However, little is known about the physiopathologic tonicity thresholds that trigger its transcriptional activity in primary cells. Wilkins et al. recently developed a transgenic mouse carry...

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Main Authors: Morancho, Beatriz, Minguillón, Jordi, Molkentin, Jeffery D, López-Rodríguez, Cristina, Aramburu, Jose
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262899/
https://ncbi.nlm.nih.gov/pubmed/18221508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-13
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