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Synthesis and Pharmacology of 1-Deoxy Analogs of CP-47,497 and CP-55,940

A series of 1-deoxy analogs of CP-47,497 (8 and 13, n = 0 to 7) and 1-deoxy analogs of CP-55,940 (9, n = 0 to 7) have been synthesized and their affinities for the cannabinoid CB(1) and CB(2) receptors have been determined. Although the majority of these compounds exhibit selectivity for the CB(2) r...

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Bibliographic Details
Main Authors: Huffman, John W., Thompson, Alicia L. S., Wiley, Jenny L., Martin, Billy R.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262798/
https://ncbi.nlm.nih.gov/pubmed/17919913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.09.033
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