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Synthesis and biological activity of 5-aza-ellipticine derivatives

Novel 5-aza-ellipticine derivatives were synthesized and tested as antitumor agents. The new compounds were prepared more readily than the analogous ellipticine derivatives, which are known to be potent anti-tumor agents Although the novel 5-aza-ellipticine derivatives are not as biologically active...

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Detalhes bibliográficos
Main Authors: Moody, Deborah L., Dyba, Marcin, Kosakowska-Cholody, Teresa, Tarasova, Nadya I., Michejda, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262287/
https://ncbi.nlm.nih.gov/pubmed/17376678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.09.093
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