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Base-pairing Properties of the Oxidized Cytosine Derivative, 5-Hydroxy Uracil

The most abundant base-substitution mutation resulting from oxidative damage to DNA is the GC to AT transition mutation. 5-hydroxyuracil (5-OHU), produced by the oxidative deamination of cystosine, has been established as the major chemical precursor for this most abundant transition mutation. Resul...

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Autores principales: Thiviyanathan, Varatharasa, Somasunderam, Anoma, Volk, David E., Hazra, Tapas K., Mitra, Sankar, Gorenstein, David G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262052/
https://ncbi.nlm.nih.gov/pubmed/18078807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.12.010
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