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Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia

Nitric oxide (NO) is known to have various biologic and pathophysiologic effects on organisms. The molecular mechanisms by which NO exerts harmful effects are unknown, although various O(2) radicals and ions that result from reactivity of NO are presumed to be involved. Here we report that adaptive...

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Main Authors: Sogawa, Kazuhiro, Numayama-Tsuruta, Keiko, Ema, Masatsugu, Abe, Manabu, Abe, Hisaku, Fujii-Kuriyama, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC22620/
https://ncbi.nlm.nih.gov/pubmed/9636155
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