Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia

Nitric oxide (NO) is known to have various biologic and pathophysiologic effects on organisms. The molecular mechanisms by which NO exerts harmful effects are unknown, although various O(2) radicals and ions that result from reactivity of NO are presumed to be involved. Here we report that adaptive...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Sogawa, Kazuhiro, Numayama-Tsuruta, Keiko, Ema, Masatsugu, Abe, Manabu, Abe, Hisaku, Fujii-Kuriyama, Yoshiaki
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1998
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9636155/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.13.7368
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