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Interactions between integrin αIIbβ3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans

The essential contribution of the antidepressant-sensitive serotonin (5-HT) transporter SERT (which is encoded by the SLC6A4 gene) to platelet 5-HT stores suggests an important role of this transporter in platelet function. Here, using SERT-deficient mice, we have established a role for constitutive...

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Detalhes bibliográficos
Main Authors: Carneiro, Ana Marin D., Cook, Edwin H., Murphy, Dennis L., Blakely, Randy D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2260909/
https://ncbi.nlm.nih.gov/pubmed/18317590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33374
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