Deposition-related sites K5/K12 in histone H4 are not required for nucleosome deposition in yeast

Histone H4 can be acetylated at N-terminal lysines K5, K8, K12, and K16, but newly synthesized H4 is diacetylated at K5/K12 in diverse organisms. This pattern is widely thought to be important for histone deposition onto replicating DNA. To investigate the importance of K5/K12 we have mutagenized th...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Ma, Xiao-Jun, Wu, Jiansheng, Altheim, Brent A., Schultz, Michael C., Grunstein, Michael
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1998
Subjects:	Biological Sciences
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22601/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9618474/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.12.6693
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