Deposition-related sites K5/K12 in histone H4 are not required for nucleosome deposition in yeast

Histone H4 can be acetylated at N-terminal lysines K5, K8, K12, and K16, but newly synthesized H4 is diacetylated at K5/K12 in diverse organisms. This pattern is widely thought to be important for histone deposition onto replicating DNA. To investigate the importance of K5/K12 we have mutagenized th...

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Bibliografiske detaljer
Main Authors: Ma, Xiao-Jun, Wu, Jiansheng, Altheim, Brent A., Schultz, Michael C., Grunstein, Michael
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22601/
https://ncbi.nlm.nih.gov/pubmed/9618474
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