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DELETION OF PRESYNAPTIC ADENOSINE A(1) RECEPTORS IMPAIRS THE RECOVERY OF SYNAPTIC TRANSMISSION AFTER HYPOXIA
Adenosine protects neurons during hypoxia by inhibiting excitatory synaptic transmission and preventing NMDA receptor activation. Using an adeno-associated viral (AAV) vector containing Cre recombinase, we have focally deleted adenosine A(1) receptors in specific hippocampal regions of adult mice. R...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2259447/ https://ncbi.nlm.nih.gov/pubmed/15837119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2004.12.009 |
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