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Transient allodynia pain models in mice for early assessment of analgesic activity

BACKGROUND AND PURPOSE: The most common preclinical models of neuropathic pain involve surgical ligation of sensory nerves, which is especially difficult in mice. Transient models of chemically sensitized allodynia are potentially useful for rapidly characterizing the analgesic profile of compounds...

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Detalhes bibliográficos
Main Authors: Gil, D W, Cheevers, C V, Donello, J E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259208/
https://ncbi.nlm.nih.gov/pubmed/17700719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707412
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