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Inhibition of matrix metalloproteinases prevents peroxynitrite-induced contractile dysfunction in the isolated cardiac myocyte
BACKGROUND AND PURPOSE: The potent oxidant peroxynitrite (ONOO(−)) induces mechanical dysfunction in the intact heart in part through activation of matrix metalloproteinase-2 (MMP-2). This effect may be independent of the proteolytic actions of MMPs on extracellular matrix proteins. The purpose of t...
Tallennettuna:
| Päätekijät: | , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2007
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2259199/ https://ncbi.nlm.nih.gov/pubmed/18071296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707621 |
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