Knockout of β(1)- and β(2)-adrenoceptors attenuates pressure overload-induced cardiac hypertrophy and fibrosis

BACKGROUND AND PURPOSE: The role of β-adrenoceptors in heart disease remains controversial. Although β-blockers ameliorate the progression of heart disease, the mechanism remains undefined. We investigated the effect of β-adrenoceptors on cardiac hypertrophic growth using β(1)- and β(2)-adrenorecept...

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Detalhes bibliográficos
Main Authors: Kiriazis, H, Wang, K, Xu, Q, Gao, X-M, Ming, Z, Su, Y, Moore, X-L, Lambert, G, Gibbs, M E, Dart, A M, Du, X-J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259198/
https://ncbi.nlm.nih.gov/pubmed/18193078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707622
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