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Myostatin promotes the terminal differentiation of embryonic muscle progenitors

Myostatin, a TGF-β family member, is an important regulator of adult muscle size. While extensively studied in vitro, the mechanisms by which this molecule mediates its effect in vivo are poorly understood. We addressed this question using chick and mouse embryos. We show that while myostatin overex...

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Detalhes bibliográficos
Main Authors: Manceau, Marie, Gros, Jérôme, Savage, Kathleen, Thomé, Virginie, McPherron, Alexandra, Paterson, Bruce, Marcelle, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259035/
https://ncbi.nlm.nih.gov/pubmed/18316481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.454408
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