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Replication of ICP0-Null Mutant Herpes Simplex Virus Type 1 Is Restricted by both PML and Sp100

Herpes simplex virus type 1 (HSV-1) mutants that fail to express the viral immediate-early protein ICP0 have a pronounced defect in viral gene expression and plaque formation in limited-passage human fibroblasts. ICP0 is a RING finger E3 ubiquitin ligase that induces the degradation of several cellu...

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Detaylı Bibliyografya
Asıl Yazarlar: Everett, Roger D., Parada, Carlos, Gripon, Philippe, Sirma, Hüseyin, Orr, Anne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258993/
https://ncbi.nlm.nih.gov/pubmed/18160441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02308-07
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