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Aromatic Amino Acids in the Juxtamembrane Domain of Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Are Important for Receptor-Dependent Virus Entry and Cell-Cell Fusion
The severe acute respiratory syndrome coronavirus (SARS-CoV) spike glycoprotein (S) is a class I viral fusion protein that binds to its receptor glycoprotein, human angiotensin converting enzyme 2 (hACE2), and mediates virus entry and cell-cell fusion. The juxtamembrane domain (JMD) of S is an aroma...
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Main Authors: | , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Society for Microbiology (ASM)
2008
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2258972/ https://ncbi.nlm.nih.gov/pubmed/18199653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01805-07 |
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