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Differential Role of Gamma Interferon in Inhibiting Pulmonary Eosinophilia and Exacerbating Systemic Disease in Fusion Protein-Immunized Mice Undergoing Challenge Infection with Respiratory Syncytial Virus

Secondary exposure to respiratory syncytial virus (RSV) can lead to immunopathology and enhanced disease in vaccinated individuals. Vaccination with individual RSV proteins influences the type of secondary RSV-specific immune response that develops upon challenge RSV infection, as well as the extent...

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Detalhes bibliográficos
Main Authors: Castilow, Elaine M., Olson, Matthew R., Meyerholz, David K., Varga, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258940/
https://ncbi.nlm.nih.gov/pubmed/18094193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01949-07
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