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Differential Role of Gamma Interferon in Inhibiting Pulmonary Eosinophilia and Exacerbating Systemic Disease in Fusion Protein-Immunized Mice Undergoing Challenge Infection with Respiratory Syncytial Virus

Secondary exposure to respiratory syncytial virus (RSV) can lead to immunopathology and enhanced disease in vaccinated individuals. Vaccination with individual RSV proteins influences the type of secondary RSV-specific immune response that develops upon challenge RSV infection, as well as the extent...

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Autors principals: Castilow, Elaine M., Olson, Matthew R., Meyerholz, David K., Varga, Steven M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258940/
https://ncbi.nlm.nih.gov/pubmed/18094193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01949-07
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