The Programmed Death-1 and Interleukin-10 Pathways Play a Down-Modulatory Role in LP-BM5 Retrovirus-Induced Murine Immunodeficiency Syndrome

Pathology due to the immune system's response to viral infections often represents a delicate balance between inhibition of viral pathogenesis and regulation of protective immunity. In susceptible C57BL/6 (B6) mice, the murine retroviral isolate LP-BM5 induces splenomegaly, hypergammaglobulinem...

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Hlavní autoři: Green, Kathy A., Okazaki, Taku, Honjo, Tasuku, Cook, W. James, Green, William R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258922/
https://ncbi.nlm.nih.gov/pubmed/18094175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01665-07
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