Structures of Two Coronavirus Main Proteases: Implications for Substrate Binding and Antiviral Drug Design

Coronaviruses (CoVs) can infect humans and multiple species of animals, causing a wide spectrum of diseases. The coronavirus main protease (M(pro)), which plays a pivotal role in viral gene expression and replication through the proteolytic processing of replicase polyproteins, is an attractive targ...

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Detalhes bibliográficos
Main Authors: Xue, Xiaoyu, Yu, Hongwei, Yang, Haitao, Xue, Fei, Wu, Zhixin, Shen, Wei, Li, Jun, Zhou, Zhe, Ding, Yi, Zhao, Qi, Zhang, Xuejun C., Liao, Ming, Bartlam, Mark, Rao, Zihe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258912/
https://ncbi.nlm.nih.gov/pubmed/18094151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02114-07
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