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Structures of Two Coronavirus Main Proteases: Implications for Substrate Binding and Antiviral Drug Design
Coronaviruses (CoVs) can infect humans and multiple species of animals, causing a wide spectrum of diseases. The coronavirus main protease (M(pro)), which plays a pivotal role in viral gene expression and replication through the proteolytic processing of replicase polyproteins, is an attractive targ...
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| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2258912/ https://ncbi.nlm.nih.gov/pubmed/18094151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02114-07 |
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