Interaction between the Human Immunodeficiency Virus Type 1 Gag Matrix Domain and Phosphatidylinositol-(4,5)-Bisphosphate Is Essential for Efficient Gag Membrane Binding

Human immunodeficiency virus type 1 (HIV-1) particle assembly mediated by the viral structural protein Gag occurs predominantly on the plasma membrane (PM). Although it is known that the matrix (MA) domain of Gag plays a major role in PM localization, molecular mechanisms that determine the location...

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Détails bibliographiques
Auteurs principaux: Chukkapalli, Vineela, Hogue, Ian B., Boyko, Vitaly, Hu, Wei-Shau, Ono, Akira
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2008
Sujets:
Structure and Assembly
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258911/
https://ncbi.nlm.nih.gov/pubmed/18094158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01614-07
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